Eshelman Insider June-July 2018 - FAO UNC Eshelman School of Pharmacy

June/July 2018 Vol 2. No. 4

The dean’s search is nearing an end. Six candidates interviewed for the position. The search committee considered the broad-based feedback received from many of you in its deliberations and submitted the names of three finalists to Provost Blouin for his consideration. Your feedback will weigh significantly in his decision, and you can be assured that he is reviewing all of it. It is expected that the provost will make his decision within the next two weeks.

Over the past several months, Mary McClurg with the assistance of Terry Kale organized groups of faculty and staff to work on refreshing the School’s Strategic Plan 2012–2017. The goal of this exercise is to update and refine the 2012-2017 plan that can serve the School through the middle of 2020, at which point in time the new dean will initiate strategic planning for the next five years. A draft of the Strategic Plan 2018–2020 has been prepared through multiple iterations among the faculty, staff and leadership of the School. The plan will be discussed and endorsed by the faculty at our faculty meeting on August 20.

The Eshelman Institute for Innovation announced a third round of funding in which 25 projects were selected for awards totaling more than $3.5 million. Of special note, this is the first time that a proposal from a member of the School staff has been funded. Congratulation to Jennifer Fox on her successful proposal. I encourage all staff to take advantage of the EII’s challenge and support to help make your innovative ideas a reality.

The School welcomed the Class of 2022 on Aug. 1 at a Connection BBQ and on Aug. 2 for a day-long orientation program. I want give special thanks to the staff of the Office of Curricular and Student Affairs and the Office of Advancement, the School leadership, faculty, staff and students who volunteered and participated in the welcoming and orientation activities.

Several individuals within the School have accepted either new or expanded leadership responsibilities. Please join me in congratulating them and thanking them for their service.

Carla White has been promoted to associate dean of organizational diversity and inclusion in recognition of her valuable contributions to date and her expanded role going forward. Under Carla’s leadership we aspire to be a national leader in promoting a diverse and inclusive community among our faculty, staff and students.
Phil Rodgers has been selected to serve as the director for interprofessional education and practice. Interprofessional education is becoming an important component of the academic programs within all health sciences schools. Its importance was elevated on the campus through the recent creation of the Office of Interprofessional Education and Practice led by Assistant Provost Meg Zomorodi. I am delighted that Phil has accepted this very important role within our School, and I want to acknowledge Kim Sanders who has been instrumental in laying the foundations for interprofessional education and practice within our School in collaboration with the School of Dentistry.
Amanda Corbett has been appointed as assistant dean for the professional curriculum. In this new position, Amanda will work closely with the Curriculum Innovation Committee and the Curriculum Implementation and Assessment Committee, as well as all key constituencies, to ensure integration of curricular innovations into the professional curriculum and seamless implementation of the residential, experiential, global and rural components of the curriculum.
Sam Lai has been named assistant director for academic innovation at the Eshelman Institute for Innovation. In this new role, Sam will help create educational initiatives promoting innovation and entrepreneurship and will contribute to new strategic initiatives and programs extending the institute’s impact. Sam oversees the execution and evolution of the Young Innovators program and the E(I) Lab program, seeking external funding to support and sustain the programs and promoting the programs through scholarship.
With the retirement of Tom Angelo, Jacqui McLaughlin has taken over the leadership of the Center for Innovative Pharmacy Education and Research as its director. Jacqui will be responsible for leading the center and ensuring strategic alignment between the work of the center and the School’s Educational Renaissance initiatives. CIPhER aims to improve the effectiveness and efficiency of curricula and instruction by providing professional development and support to faculty, clinical preceptors, postgraduate fellows, residents and teaching assistants. CIPhER also assists faculty and others in their educational research and scholarship.
Ashley Qi has been selected as the associate director of China initiatives. In this newly created position, she will assist with the School’s academic initiatives in China. Initially, her primary focus will be to lead our due diligence efforts for developing a pharmacy and pharmaceutical sciences education and research institution in partnership with a major university

I am pleased to report that our Resiliency and Well-Being Task Force held its inaugural meeting and kickoff on June 26. The task force will assess the major factors that contribute to the stress among our students, staff, and faculty, study best practices and make recommendations for creating and sustaining a healthy work environment. We have had nearly 70 individuals volunteer to be part of the team, and I am very grateful and proud of the enthusiasm our students, faculty and staff have shown for this effort.

Finally, the Young Innovators Program Research Symposium will be held on Friday, Aug. 10, at 9 a.m. in Kerr Hall. I hope many of you will be able to attend.

Dhiren Thakker
Ferguson Distinguished Professor
Interim Dean

School News

Seyerle Joins DPOP as Assistant Professor

Amanda Seyerle, Ph.D., has been hired as a tenure-track assistant professor at the UNC Eshelman School of Pharmacy, starting July 30. Seyerle will join the Division of Pharmaceutical Outcomes and Policy.

Seyerle earned her Master of Science in Public Health in 2013 and her Ph.D. in epidemiology in 2016, both from the UNC Gillings School of Global Public Health. She is a graduate of the University of Michigan, where she studied anthropological and molecular genetics, as well as history.

Albert Bowers Promoted to Associate Professor

Albert Bowers, Ph.D., a faculty member in the Division of Chemical Biology and Medicinal Chemistry, has been promoted to the rank of associate professor at the UNC Eshelman School of Pharmacy. Bowers is a member of the UNC Lineberger Comprehensive Cancer Center and an affiliate member of the School’s Center for Integrative Chemical Biology and Drug Discovery.

Bowers’ research focuses on harnessing natural product biosynthesis to make next generation therapeutics. Researchers in the Bowers Lab, who go by the Twitter handle @BowersRangers, use insights and chemistries from natural product biosynthesis to facilitate the discovery and development of new natural product-like peptide macrocycles. This work has provided new avenues and technologies for development of peptide macrocycle-based therapeutics as cancer chemotherapies and antibiotics.

Megan Roberts Joins DPOP as Assistant Professor

Megan Roberts, Ph.D., has been hired as a tenure-track assistant professor at the UNC Eshelman School of Pharmacy in the the Division of Pharmaceutical Outcomes and Policy.

Roberts earned her Ph.D. in health policy and management from the UNC Gillings School of Global Public Health in 2015. She received her undergraduate degree from Davidson College, where she studied biology and Spanish.

Resiliency Team to Support Mental Health, Well-Being at School

The UNC Eshelman School of Pharmacy’s Resiliency and Well-Being Task Force held its inaugural meeting at a June 26 retreat at the N.C. Botanical Gardens.

The team, chaired by Mollie Scott, Pharm.D., and Brad Wingo, M.Ed., is charged with creating innovative ways to foster the mental and physical well-being of School students, faculty and staff. Scott is the regional associate dean for the School’s Asheville satellite campus. Wingo is the director of curricular and student affairs.

CIPS Wins Awards for Web Design and Video Production

Members from the UNC Eshelman School of Pharmacy’s Center for Innovation in Pharmacy Simulation won four Hermes awards and two Telly Awards for web design and videography. An interactive webpage designed by CIPS won four Hermes Creative Awards on May 18. The page, designed for the Community Pharmacy Foundation, outlines principles of team-based health care.

Jason Whitley, M.S.; Joel Floyd, M.S.; and Catherine MacAllister, M.Ed. designed the webpage. It was based on research conducted by postdoctoral researcher Chelsea Renfro, Pharm.D. Multimedia producer Kevin Robinson received a Hermes Creative Gold Award in the category of recruitment videos.

In the News

AI Learns to Create Drugs From Scratch | Geek.com — Alex Tropsha, Ph.D.; Olexander Isayev, Ph.D.; Mariya Popova
(Also Phys.org, Science Daily and WRAL TechWire)

Pharmacists forge an expanded role in patient-centered care | MultiBrief.com — Charles Lee

FDA approves first cannabis-based drug | CNN.com — Shauna Garris, Pharm.D.

A Gene Therapy Appears To Replace Missing Protein In Muscular Dystrophy Patients | Forbes.com — Xiao Xiao, Ph.D.

School Updates

New Parking Permits

Aug. 15 is the beginning of the 2018–2019 permit year. Remember to display the new permit beginning Aug. 15. You can throw your old one away.

You must register the license plate numbers of all vehicles you plan to park on campus with Transportation and Parking for affiliates. You can add vehicle information by visiting http://move.unc.edu/about/online-services/.

New Passwords for PSK Wifi

The passwords for the UNC-PSK and UNC-PSK Guest wireless networks will change Monday, Aug. 13, at 6:30 a.m. This change does not affect the Eduroam network. The UNC-PSK passphrase can be found at https://help.unc.edu/help/what-is-the-unc-psk-ssid/. The UNC-PSK Guest passphrase can be found at https://help.unc.edu/help/unc-guest-psk-ssid/.

Resources

FAOpharmacy.unc.edu is the website to visit for information on the School’s internal processes and procedures, including finance, administration and operations. There you’ll find resources such as the School’s master calendar and travel and purchasing workflows.

How to Get Help

Information technology and facilities? Email itsop@unc.edu
Finance? Email esopfinance@unc.edu.
Educational technology? Email techcore@unc.edu.
Marketing and communications including announcements to the School listservs or website edits? Go to https://pharmacy.unc.edu/marcom.

Social Media

Find the School on Facebook, Twitter and LinkedIn. If you’re curious about incorporating social media into your role at the School, contact the Office of Marketing and Communications for a consultation by going to https://pharmacy.unc.edu/marcom and filling out a request form.

Upcoming Events

Aug. 8 Employee Photo Session

Aug. 9 Annual Durham Bulls Outing

Aug. 10 Young Innovators Program Research Symposium

Aug. 10 Pharmacy Friday

Aug. 15 Pharmaceutical Sciences Graduate Program Orientation

Aug. 22 Employee Photo Session

Aug. 28 Monthly K drive Content Deletion

Aug. 31 Pharmacy Friday

Sept. 2 Employee Photo Session

Sept 7 Pharmacy Friday

New Grants and Contracts

June

David Lawrence, American Heart Association, $53,688, FELLOW: B VICKERMAN Use of Vitamin B12 to Release Multiple Angiogenic Factors with Long Wavelength Light to Achieve Therapeutic Angiogenesis
Kuo-Hsiung Lee, NIH National Institute of Allergy and Infectious Diseases, $483,933, Plant Anti-HIV Agents
Marina Sokolsky, St Baldrick’s Foundation, $99,951, Improving outcomes for medulloblastoma by targeting 2 distinct points in the SHH signaling pathway using novel nanoparticle formulations of pablociclib and vismodegib
Tim Wiltshire, American Heart Association, $26,844.00 , FELLOW:OLVIA DONG Pharmacogenomic Testing with DNA2RXTM in Cardiac Catheterization Laboratory Patients

July

Kristy Ainslie, IMMvention Therapeutix, Inc, $104,140, STTR: Advancing Formulation of STING agonist for Universal Flu Vaccine
Jeff Aube, University of Kansas Center for Research, Inc., $80,817, Molecular Cancer Therapy Targeting HuR-ARE Interaction
Kim Brouwer, NIH National Institute of General Medical Sciences, $696,677, UNC-Duke-Hamner Collaborative Clinical Pharmacology Postdoctoral Training Program
Julie Dumond, University of California at San Francisco, $7,433, Epigenomics of ethnic and racial disparities in ARV exposure and treatment outcomes
Stephen Frye, NIH National Institute of General Medical Sciences, $416,687, Discovery of Chemical Probes for Chromatin Readers
Nate Hathaway, NIH National Institute of General Medical Sciences, $302,270, Mechanism of HP1-mediated heterochromatin assembly and durability in live cells
Olexandr Isayev, National Science Foundation, $350,836, Collaborative Research: CDS&E: Development and application of accurate, transferable and extensible deep neural network potentials for molecules and reactions
Michael Jay, NIH National Institute of General Medical Sciences, $65,346, FELLOW:J PRYBYLSKI Gadolinium Deposition in the Brain Following Administration of MRI Contrast Agents: Mechanism of Uptake, Determination of Gd Species and Relation to Extravasation
Alexander Kabanov, NIH National Cancer Institute, $409,752, Carolina Cancer Nanotechnology Training Program
Sam Lai, National Science Foundation, $331,063, Dynamic tuning of barrier properties of hydrogels using weakly adhesive third-party crosslinkers
Sam Lai, NIH National Heart, Lung, and Blood Institute, $633,547, Overcoming anti-PEG immunity to restore prolonged circulation and efficacy of PEGylated therapeutics

New Publications

CBMC – June

Song, W., Shen, L., Wang, Y., Liu, Q., Goodwin, T.J., Li, J., Dorosheva, O., Liu, T., Liu, R., Huang, L., Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap, (2018) Nature Communications, 9 (1), art. no. 2237, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048342701&doi=10.1038%2fs41467-018-04605-x&partnerID=40&md5=eb640f0e8fdb2f9297ab9d1254ede9f3
Gossett, E., Toher, C., Oses, C., Isayev, O., Legrain, F., Rose, F., Zurek, E., Carrete, J., Mingo, N., Tropsha, A., Curtarolo, S. AFLOW-ML: A RESTful API for machine-learning predictions of materials properties. (2018) Computational Materials Science, 152, pp. 134-145. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047645950&doi=10.1016%2fj.commatsci.2018.03.075&partnerID=40&md5=13571b3ed36645d6ca2669b9f45ba05b
Miller, C.M., Xu, Y., Kudrna, K.M., Hass, B.E., Kellar, B.M., Egger, A.W., Liu, J., Harris, E.N. 3-O sulfation of heparin leads to hepatotropism and longer circulatory half-life. (2018) Thrombosis Research, 167, pp. 80-87. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047256019&doi=10.1016%2fj.thromres.2018.05.018&partnerID=40&md5=d089de6cb8a807e56e4231e7895c25d2
Alves, V.M., Golbraikh, A., Capuzzi, S.J., Liu, K., Lam, W.I., Korn, D.R., Pozefsky, D., Andrade, C.H., Muratov, E.N., Tropsha, A. Multi-Descriptor Read Across (MuDRA): A Simple and Transparent Approach for Developing Accurate Quantitative Structure-Activity Relationship Models (2018) Journal of Chemical Information and Modeling, 58 (6), pp. 1214-1223. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047993665&doi=10.1021%2facs.jcim.8b00124&partnerID=40&md5=40d57211597f88a5d42ffd196407a983
Ling, Y., Yang, Q.-X., Teng, Y.-N., Chen, S., Gao, W.-J., Guo, J., Hsu, P.-L., Liu, Y., Morris-Natschke, S.L., Hung, C.-C., Lee, K.-H. Development of novel amino-quinoline-5,8-dione derivatives as NAD(P)H:quinone oxidoreductase 1 (NQO1) inhibitors with potent antiproliferative activities (2018) European Journal of Medicinal Chemistry, 154, pp. 199-209. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047348456&doi=10.1016%2fj.ejmech.2018.05.025&partnerID=40&md5=8bacdfe4f127811863391afb7b564e44
O’Banion, C.P., Lawrence, D.S. Optogenetics: A Primer for Chemists (2018) ChemBioChem, 19 (12), pp. 1201-1216. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047426690&doi=10.1002%2fcbic.201800013&partnerID=40&md5=22acc30e9c0af6b88402656dd77c7a95
Fehl, C., Vogt, C.D., Yadav, R., Li, K., Scott, E.E., Aubé, J. Structure-Based Design of Inhibitors with Improved Selectivity for Steroidogenic Cytochrome P450 17A1 over Cytochrome P450 21A2 (2018) Journal of Medicinal Chemistry, 61 (11), pp. 4946-4960. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048520770&doi=10.1021%2facs.jmedchem.8b00419&partnerID=40&md5=098369ee2d63300d05666128429909b7
La, M.K., Sedykh, A., Fourches, D., Muratov, E., Tropsha, A. Predicting Adverse Drug Effects from Literature- and Database-Mined Assertions (2018) Drug Safety, pp. 1-14. Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048030879&doi=10.1007%2fs40264-018-0688-5&partnerID=40&md5=5dc039f26ed56576c08324d980e76846
Zhao, Y., Yang, J.Y., Thieker, D.F., Xu, Y., Zong, C., Boons, G.-J., Liu, J., Woods, R.J., Moremen, K.W., Amster, I.J. A Traveling Wave Ion Mobility Spectrometry (TWIMS) Study of the Robo1-Heparan Sulfate Interaction (2018) Journal of the American Society for Mass Spectrometry, 29 (6), pp. 1153-1165. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048699042&doi=10.1007%2fs13361-018-1903-4&partnerID=40&md5=92f684d0cd2fbf4240481af7d07ef067
Pariollaud, M., Gibbs, J.E., Hopwood, T.W., Brown, S., Begley, N., Vonslow, R., Poolman, T., Guo, B., Saer, B., Jones, D.H., Tellam, J.P., Bresciani, S., Tomkinson, N.C.O., Wojno-Picon, J., Cooper, A.W.J., Daniels, D.A., Trump, R.P., Grant, D., Zuercher, W., Willson, T.M., MacDonald, A.S., Bolognese, B., Podolin, P.L., Sanchez, Y., Loudon, A.S.I., Ray, D.W. Circadian clock component REV-ERBa controls homeostatic regulation of pulmonary inflammation (2018) Journal of Clinical Investigation, 128 (6), pp. 2281-2296. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048260311&doi=10.1172%2fJCI93910&partnerID=40&md5=e747ee55fdc592c850cb93dedc7ed44b
Frankowski, K.J., Wang, C., Patnaik, S., Schoenen, F.J., Southall, N., Li, D., Teper, Y., Sun, W., Kandela, I., Hu, D., Dextras, C., Knotts, Z., Bian, Y., Norton, J., Titus, S., Lewandowska, M.A., Wen, Y., Farley, K.I., Griner, L.M., Sultan, J., Meng, Z., Zhou, M., Vilimas, T., Powers, A.S., Kozlov, S., Nagashima, K., Quadri, H.S., Fang, M., Long, C., Khanolkar, O., Chen, W., Kang, J., Huang, H., Chow, E., Goldberg, E., Feldman, C., Xi, R., Kim, H.R., Sahagian, G., Baserga, S.J., Mazar, A., Ferrer, M., Zheng, W., Shilatifard, A., Aubé, J., Rudloff, U., Marugan, J.J., Huang, S. Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis (2018) Science Translational Medicine, 10 (441), art. no. eaap8307, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047366817&doi=10.1126%2fscitranslmed.aap8307&partnerID=40&md5=97c8d3fb921db9c0e06666860a3c0c72
Puhl-Rubio, A.C., Stashko, M.A., Wang, H., Hardy, P.B., Tyagi, V., Li, B., Wang, X., Kireev, D., Jessen, H.J., Frye, S.V., Shears, S.B., Pearce, K.H. Use of Protein Kinase–Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors (2018) SLAS Discovery, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047834676&doi=10.1177%2f2472555218775323&partnerID=40&md5=25d4e4b3888c7d0e23cf9d3a793fa059
Hsieh, M.-T., Huang, L.-J., Wu, T.-S., Lin, H.-Y., Morris-Natschke, S.L., Lee, K.-H., Kuo, S.-C. Synthesis and antitumor activity of bis(hydroxymethyl)propionate analogs of pterostilbene in cisplatin-resistant human oral cancer cells (2018) Bioorganic and Medicinal Chemistry, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048325903&doi=10.1016%2fj.bmc.2018.06.011&partnerID=40&md5=b4fdb9039fca89e29684533b20be9a39
Asquith, C.R.M., Godoi, P.H., Cou ago, R.M., Laitinen, T., Scott, J.W., Langendorf, C.G., Oakhill, J.S., Drewry, D.H., Zuercher, W.J., Koutentis, P.A., Willson, T.M., Kalogirou, A.S. 1,2,6-thiadiazinones as novel narrow spectrum calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) Inhibitors (2018) Molecules, 23 (5), art. no. 1221, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047477636&doi=10.3390%2fmolecules23051221&partnerID=40&md5=b9e120a5a9004b5f2574eb638648852c

CBMC – July

Zhang, Q., Hu, X.-F., Xin, M.-M., Liu, H.-B., Sun, L.-J., Morris-Natschke, S.L., Chen, Y., Lee, K.-H.Antidiabetic potential of the ethyl acetate extract of Physalis alkekengi and chemical constituents identified by HPLC-ESI-QTOF-MS (2018) Journal of Ethnopharmacology, 225, pp. 202-210. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049981536&doi=10.1016%2fj.jep.2018.07.007&partnerID=40&md5=b1b7ae751f5bd6db186545e872b00587
Liu, Q., Li, W., Huang, L., Asada, Y., Morris-Natschke, S.L., Chen, C.-H., Lee, K.-H., Koike, K.Identification, structural modification, and dichotomous effects on human immunodeficiency virus type 1 (HIV-1) replication of ingenane esters from Euphorbia kansui(2018) European Journal of Medicinal Chemistry, 156, pp. 618-627. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050111088&doi=10.1016%2fj.ejmech.2018.07.020&partnerID=40&md5=de200647580db6c7aed664fcf7cd7e45
Hull-Ryde, E.A., Porter, M.A., Fowler, K.A., Kireev, D., Li, K., Simpson, C.D., Sassano, M.F., Suto, M.J., Pearce, K.H., Janzen, W., Coghill, J.M. Identification of Cosalane as an Inhibitor of Human and Murine CC–Chemokine Receptor 7 Signaling via a High-Throughput Screen (2018) SLAS Discovery, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049831768&doi=10.1177%2f2472555218780917&partnerID=40&md5=5b1e0fadc5442c23ba2d1be9666d9882
Weiss, D.R., Karpiak, J., Huang, X.-P., Sassano, M.F., Lyu, J., Roth, B.L., Shoichet, B.K.Selectivity Challenges in Docking Screens for GPCR Targets and Anti-Targets(2018) Journal of Medicinal Chemistry, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049861584&doi=10.1021%2facs.jmedchem.8b00718&partnerID=40&md5=23a09d342b734aab51e58cf9ce05aec9
Sun, Y.-P., Jin, W.-F., Wang, Y.-Y., Wang, G., Morris-Natschke, S.L., Liu, J.-S., Wang, G.-K., Lee, K.-H. Chemical structures and biological activities of limonoids from the genus swietenia (meliaceae) (2018) Molecules, 23 (7), art. no. 1588, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049440413&doi=10.3390%2fmolecules23071588&partnerID=40&md5=6a0f815161ca0c5e81afbd1735927fc4

DPET – June

Zhu, P., Zhang, J., Chen, Y., Yin, S., Su, M., Xie, G., Brouwer, K.L.R., Liu, C., Lan, K., Jia, W. Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids (2018) Analytical and Bioanalytical Chemistry, 410 (21), pp. 5287-5300. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048572769&doi=10.1007%2fs00216-018-1183-7&partnerID=40&md5=d2ede839d6f4fcdc33aa4787dc2eab41
Lin, Y.-W., Yu, H.H., Zhao, J., Han, M.-L., Zhu, Y., Akter, J., Wickremasinghe, H., Walpola, H., Wirth, V., Rao, G.G., Forrest, A., Velkov, T., Li, J. Polymyxin b in combination with enrofloxacin exerts synergistic killing against extensively drug-resistant pseudomonas aeruginosa (2018) Antimicrobial Agents and Chemotherapy, 62 (6), art. no. e00028-18, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047649622&doi=10.1128%2fAAC.00028-18&partnerID=40&md5=31691eae4b14bc83aa8c5261c9956e26
Karageorgis, A., Lenhard, S.C., Yerby, B., Forsgren, M.F., Liachenko, S., Johansson, E., Pilling, M.A., Peterson, R.A., Yang, X., Williams, D.P., Ungersma, S.E., Morgan, R.E., Brouwer, K.L.R., Jucker, B.M., Hockings, P.D. A multi-center preclinical study of gadoxetate DCE-MRI in rats as a biomarker of drug induced inhibition of liver transporter function (2018) PLoS ONE, 13 (5), art. no. e0197213, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047323430&doi=10.1371%2fjournal.pone.0197213&partnerID=40&md5=4214ef2cc46a0bf1269cdeed90adec63
Dong, O.M., Li, A., Suzuki, O., Oni-Orisan, A., Gonzalez, R., Stouffer, G.A., Lee, C.R., Wiltshire, T. Projected impact of a multigene pharmacogenetic test to optimize medication prescribing in cardiovascular patients (2018) Pharmacogenomics, 19 (9), pp. 771-782. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048090054&doi=10.2217%2fpgs-2018-0049&partnerID=40&md5=6e7ee40044c64f9c27baa8b7ad1e81dc

DPET — July

McSweeney, M.D., Wessler, T., Price, L.S.L., Ciociola, E.C., Herity, L.B., Piscitelli, J.A., Zamboni, W.C., Forest, M.G., Cao, Y., Lai, S.K. A minimal physiologically based pharmacokinetic model that predicts anti-PEG IgG-mediated clearance of PEGylated drugs in human and mouse (2018) Journal of Controlled Release, 284, pp. 171-178. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049037038&doi=10.1016%2fj.jconrel.2018.06.002&partnerID=40&md5=17700d7c46ffb24c3720518d6b380fc4
Sherwin, J., Thompson, E., Hill, K.D., Watt, K., Lodge, A.J., Gonzalez, D., Hornik, C.P. Clinical pharmacology considerations for children supported with ventricular assist devices (2018) Cardiology in the Young, pp. 1-9. Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049899006&doi=10.1017%2fS1047951118001075&partnerID=40&md5=7cb1e09d0af834d284b80ad721d5c749
Lakota, E.A., Landersdorfer, C.B., Nation, R.L., Li, J., Kaye, K.S., Rao, G.G., Forrest, A. Personalizing Polymyxin B dosing using an adaptive feedback control algorithm (2018) Antimicrobial Agents and Chemotherapy, 62 (7), art. no. e00483-18, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049019826&doi=10.1128%2fAAC.00483-18&partnerID=40&md5=b99f724c4195497c2efdded226d9e2b6
Stump, S.E., Whang, Y.E., Crona, D.J. Cabozantinib-induced serum creatine kinase elevation and musculoskeletal complaints (2018) Investigational New Drugs, pp. 1-4. Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049128511&doi=10.1007%2fs10637-018-0629-2&partnerID=40&md5=c6e1bfb5a401b1c01e0042ea6da38269
Greene, J.M., Fuller, K.A., Persky, A.M. Practical tips for integrating clinical relevance into foundational science courses (2018) American Journal of Pharmaceutical Education, 82 (5), art. no. 6603, pp. 376-381. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049243441&doi=10.5688%2fajpe6603&partnerID=40&md5=2e9415456277590e46a52665fb32e6c8

DPMP — June

Xiao, W., Gao, G., Ling, C., Herzog, R.W., Xiao, X., Samulski, R.J.Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates (2018) Nature Medicine, 24 (6), p. 699. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048015826&doi=10.1038%2fs41591-018-0062-2&partnerID=40&md5=ebd25515ee3eff98996294673e4cf853
Jonas, A.M., Glinel, K., Behrens, A., Anselmo, A.C., Langer, R.S., Jaklenec, A. Controlling the Growth of Staphylococcus epidermidis by Layer-By-Layer Encapsulation (2018) ACS Applied Materials and Interfaces, 10 (19), pp. 16250-16259. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047304067&doi=10.1021%2facsami.8b01988&partnerID=40&md5=9d5f0b5884b262bcb649e0319473219d
Johnson, M.M., Ainslie, K.M. Vaccines for the Prevention of Melioidosis and Glanders (2017) Current Tropical Medicine Reports, 4 (3), pp. 136-145. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048525716&doi=10.1007%2fs40475-017-0121-7&partnerID=40&md5=1a487456042248823478e5c60beed1b1 DPMP — July
Bulaklak, K., Xiao, B., Qiao, C., Li, J., Patel, T., Jin, Q., Li, J., Xiao, X. MicroRNA-206 Downregulation Improves Therapeutic Gene Expression and Motor Function in mdx Mice (2018) Molecular Therapy – Nucleic Acids, 12, pp. 283-293. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048750144&doi=10.1016%2fj.omtn.2018.05.011&partnerID=40&md5=fa7defa55fb0e58923da28d67477d61c
McSweeney, M.D., Wessler, T., Price, L.S.L., Ciociola, E.C., Herity, L.B., Piscitelli, J.A., Zamboni, W.C., Forest, M.G., Cao, Y., Lai, S.K. A minimal physiologically based pharmacokinetic model that predicts anti-PEG IgG-mediated clearance of PEGylated drugs in human and mouse (2018) Journal of Controlled Release, 284, pp. 171-178. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049037038&doi=10.1016%2fj.jconrel.2018.06.002&partnerID=40&md5=17700d7c46ffb24c3720518d6b380fc4
Qiu, K., Durham, P.G., Anselmo, A.C. Inorganic nanoparticles and the microbiome (2018) Nano Research, pp. 1-19. Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049830156&doi=10.1007%2fs12274-018-2137-2&partnerID=40&md5=cb43b89a69aac9c7d53ed956da487ffd
Schroeder, H.A., Nunn, K.L., Schaefer, A., Henry, C.E., Lam, F., Pauly, M.H., Whaley, K.J., Zeitlin, L., Humphrys, M.S., Ravel, J., Lai, S.K. Herpes simplex virus-binding IgG traps HSV in human cervicovaginal mucus across the menstrual cycle and diverse vaginal microbial composition (2018) Mucosal Immunology, pp. 1-10. Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049640907&doi=10.1038%2fs41385-018-0054-z&partnerID=40&md5=bc69cff3084a019951de54f830c821cf
Okolie, O., Irvin, D.M., Bago, J.R., Sheets, K., Satterlee, A., Carey-Ewend, A.G., Lettry, V., Dumitru, R., Elton, S., Ewend, M.G., Ryan Miller, C., Hingtgen, S.D. Intra-cavity stem cell therapy inhibits tumor progression in a novel murine model of medulloblastoma surgical resection (2018) PLoS ONE, 13 (7), art. no. e0198596, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049629136&doi=10.1371%2fjournal.pone.0198596&partnerID=40&md5=52b41436497d62e58bb576dddfd632d3
Dorman, D.C., Foster, M.L., Olesnevich, B., Bolon, B., Castel, A., Sokolsky-Papkov, M., Mariani, C.L. Toxicity associated with ingestion of a polyacrylic acid hydrogel dog pad (2018) Journal of Veterinary Diagnostic Investigation, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048774294&doi=10.1177%2f1040638718782583&partnerID=40&md5=ec38c88f4f4abe75c36899fa3428ea2b
Buglak, N.E., Batrakova, E.V., Mota, R., Bahnson, E.S.M. Insights on localized and systemic delivery of redox-based therapeutics (2018) Oxidative Medicine and Cellular Longevity, 2018, art. no. 2468457, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048898155&doi=10.1155%2f2018%2f2468457&partnerID=40&md5=144a054a55bcbf9106c590a618a79447
Hou, L., Liu, Q., Shen, L., Liu, Y., Zhang, X., Chen, F., Huang, L. Nano-delivery of fraxinellone remodels tumor microenvironment and facilitates therapeutic vaccination in desmoplastic melanoma (2018) Theranostics, 8 (14), pp. 3781-3796. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049205168&doi=10.7150%2fthno.24821&partnerID=40&md5=1258b459df1ccdb1d54044305f683d0e
Ye, Y., Wang, C., Zhang, X., Hu, Q., Zhang, Y., Liu, Q., Wen, D., Milligan, J., Bellotti, A., Huang, L., Dotti, G., Gu, Z. A melanin-mediated cancer immunotherapy patch (2017) Science immunology, 2 (17), . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049283109&doi=10.1126%2fsciimmunol.aan5692&partnerID=40&md5=e105a45a2827cf32fb9c1a9af1f75cdc

DPMP — July

Bulaklak, K., Xiao, B., Qiao, C., Li, J., Patel, T., Jin, Q., Li, J., Xiao, X. MicroRNA-206 Downregulation Improves Therapeutic Gene Expression and Motor Function in mdx Mice (2018) Molecular Therapy – Nucleic Acids, 12, pp. 283-293. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048750144&doi=10.1016%2fj.omtn.2018.05.011&partnerID=40&md5=fa7defa55fb0e58923da28d67477d61c
McSweeney, M.D., Wessler, T., Price, L.S.L., Ciociola, E.C., Herity, L.B., Piscitelli, J.A., Zamboni, W.C., Forest, M.G., Cao, Y., Lai, S.K. A minimal physiologically based pharmacokinetic model that predicts anti-PEG IgG-mediated clearance of PEGylated drugs in human and mouse (2018) Journal of Controlled Release, 284, pp. 171-178. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049037038&doi=10.1016%2fj.jconrel.2018.06.002&partnerID=40&md5=17700d7c46ffb24c3720518d6b380fc4
Qiu, K., Durham, P.G., Anselmo, A.C. Inorganic nanoparticles and the microbiome (2018) Nano Research, pp. 1-19. Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049830156&doi=10.1007%2fs12274-018-2137-2&partnerID=40&md5=cb43b89a69aac9c7d53ed956da487ffd
Schroeder, H.A., Nunn, K.L., Schaefer, A., Henry, C.E., Lam, F., Pauly, M.H., Whaley, K.J., Zeitlin, L., Humphrys, M.S., Ravel, J., Lai, S.K. Herpes simplex virus-binding IgG traps HSV in human cervicovaginal mucus across the menstrual cycle and diverse vaginal microbial composition (2018) Mucosal Immunology, pp. 1-10. Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049640907&doi=10.1038%2fs41385-018-0054-z&partnerID=40&md5=bc69cff3084a019951de54f830c821cf
Okolie, O., Irvin, D.M., Bago, J.R., Sheets, K., Satterlee, A., Carey-Ewend, A.G., Lettry, V., Dumitru, R., Elton, S., Ewend, M.G., Ryan Miller, C., Hingtgen, S.D. Intra-cavity stem cell therapy inhibits tumor progression in a novel murine model of medulloblastoma surgical resection (2018) PLoS ONE, 13 (7), art. no. e0198596, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049629136&doi=10.1371%2fjournal.pone.0198596&partnerID=40&md5=52b41436497d62e58bb576dddfd632d3
Dorman, D.C., Foster, M.L., Olesnevich, B., Bolon, B., Castel, A., Sokolsky-Papkov, M., Mariani, C.L. Toxicity associated with ingestion of a polyacrylic acid hydrogel dog pad (2018) Journal of Veterinary Diagnostic Investigation, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048774294&doi=10.1177%2f1040638718782583&partnerID=40&md5=ec38c88f4f4abe75c36899fa3428ea2b
Buglak, N.E., Batrakova, E.V., Mota, R., Bahnson, E.S.M. Insights on localized and systemic delivery of redox-based therapeutics (2018) Oxidative Medicine and Cellular Longevity, 2018, art. no. 2468457, . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048898155&doi=10.1155%2f2018%2f2468457&partnerID=40&md5=144a054a55bcbf9106c590a618a79447
Hou, L., Liu, Q., Shen, L., Liu, Y., Zhang, X., Chen, F., Huang, L. Nano-delivery of fraxinellone remodels tumor microenvironment and facilitates therapeutic vaccination in desmoplastic melanoma (2018) Theranostics, 8 (14), pp. 3781-3796. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049205168&doi=10.7150%2fthno.24821&partnerID=40&md5=1258b459df1ccdb1d54044305f683d0e
Ye, Y., Wang, C., Zhang, X., Hu, Q., Zhang, Y., Liu, Q., Wen, D., Milligan, J., Bellotti, A., Huang, L., Dotti, G., Gu, Z. A melanin-mediated cancer immunotherapy patch (2017) Science immunology, 2 (17), . https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049283109&doi=10.1126%2fsciimmunol.aan5692&partnerID=40&md5=e105a45a2827cf32fb9c1a9af1f75cdc

DPOP — July

Carpenter, D.M., Dhamanaskar, A.K., Gallegos, K.L., Shepherd, G., Mosley, S.L., Roberts, C.A. Factors associated with how often community pharmacists offer and dispense naloxone (2018) Research in Social and Administrative Pharmacy, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049740073&doi=10.1016%2fj.sapharm.2018.07.008&partnerID=40&md5=bf9121ee32823cf8d5f87eb31cc4c09a

PACE — JUNE

Livet, M., Haines, S.T., Curran, G.M., Seaton, T.L., Ward, C.S., Sorensen, T.D., Roth McClurg, M.Implementation Science to Advance Care Delivery: A Primer for Pharmacists and Other Health Professionals (2018) Pharmacotherapy, 38 (5), pp. 490-502. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048575576&doi=10.1002%2fphar.2114&partnerID=40&md5=333a5b71d940fcda1d042da68b5c5446
Murry, L., Gerleman, B., Urick, B., Urmie, J. Third-party reimbursement for generic prescription drugs: The prevalence of below-cost reimbursement in an environment of maximum allowable cost–based reimbursement (2018) Journal of the American Pharmacists Association, 58 (4), pp. 421-425. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048593132&doi=10.1016%2fj.japh.2018.04.018&partnerID=40&md5=1db5033fa16ece4f585edafdef2ce2b9

PACE — July

Lewis, T.D., Dehne, K.A., Morbitzer, K., Rhoney, D.H., Olm-Shipman, C., Jordan, J.D. Correction to: Influence of Single-Dose Antibiotic Prophylaxis for Early-Onset Pneumonia in High-Risk Intubated Patients (2018) Neurocritical Care, p. 1. Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049620315&doi=10.1007%2fs12028-018-0580-2&partnerID=40&md5=a89b449e9a77d827f0452597444910bc
Drake, E.S., Harris, D.K., Marciniak, M.W. Community pharmacist–led intervention to identify persons with diabetes not on statin therapy (2018) Journal of the American Pharmacists Association, 58 (4), pp. S125-S130. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049653598&doi=10.1016%2fj.japh.2018.05.010&partnerID=40&md5=170080e8d9b32c7be8cca66021fba3f6
Rudolph, S.E., Branham, A.R., Rhodes, L.A., Hayes, H.“., Jr, Moose, J.S., Marciniak, M.W. Identifying barriers to dispensing naloxone: A survey of community pharmacists in North Carolina (2018) Journal of the American Pharmacists Association, 58 (4), pp. S55-S58.e3. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049622345&doi=10.1016%2fj.japh.2018.04.025&partnerID=40&md5=45d6ee4e199a0d0d937fa39c527517e7
Clifton, C.L., Branham, A.R., Hayes, H.“., Jr, Moose, J.S., Rhodes, L.A., Marciniak, M.W. Financial impact of patients enrolled in a medication adherence program at an independent community pharmacy (2018) Journal of the American Pharmacists Association, 58 (4), pp. S109-S113. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049645712&doi=10.1016%2fj.japh.2018.04.022&partnerID=40&md5=20208a66d723e9d89a92df7ac7f35a0a
Fay, A.E., Ferreri, S.P., Shepherd, G., Lundeen, K., Tong, G.L., Pfeiffenberger, T. Care team perspectives on community pharmacy enhanced services (2018) Journal of the American Pharmacists Association, 58 (4), pp. S83-S88.e3. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049627671&doi=10.1016%2fj.japh.2018.05.009&partnerID=40&md5=993b9580bb400f3d62b4ecb1a2a73336
Westberg, S.M., Beatty, S.J., Corona, A.R., Deines, S., Gunning, K.M., Gurgle, H.E., Holtan, H.S., Marciniak, M.W., McConnell, K.J., McGivney, M.A.S., Patel, R.J. Residency pathways to ambulatory care practice: Essential insights for students, residents, and educators (2018) Journal of the American Pharmacists Association, 58 (4), pp. 372-376. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049423774&doi=10.1016%2fj.japh.2017.08.013&partnerID=40&md5=4700e06e95250397f3d8340c006fa629
Gatwood, J., Hohmeier, K., Farr, G., Eckel, S. A comparison of approaches to student pharmacist business planning in pharmacy practice management (2018) American Journal of Pharmaceutical Education, 82 (5), art. no. 6279, pp. 401-409. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049246775&doi=10.5688%2fajpe6279&partnerID=40&md5=3c6aae4c4b3d2ecff928231f78ba33b5
Lewis, T.D., Dehne, K.A., Morbitzer, K., Rhoney, D.H., Olm-Shipman, C., Dedrick Jordan, J. Influence of Single-Dose Antibiotic Prophylaxis for Early-Onset Pneumonia in High-Risk Intubated Patients (2018) Neurocritical Care, 28 (3), pp. 362-369. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049136888&doi=10.1007%2fs12028-017-0490-8&partnerID=40&md5=071f27e34a6432703c5f51ef1c22f897
Hawes, E.M., Pinelli, N.R., Sanders, K.A., Lipshutz, A.M., Tong, G., Sievers, L.S., Chao, S., Gwynne, M. Post-Hospital Discharge Care: A Retrospective Cohort Study Exploring the Value of Pharmacist-Enhanced Care and Describing Medication-Related Problems (2018) North Carolina medical journal, 79 (1), pp. 4-13. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049234147&doi=10.18043%2fncm.79.1.4&partnerID=40&md5=d4a88c207cbcd923657d012a054ef5f0
Renfro, C.P., Patti, M., Ballou, J.M., Ferreri, S.P. Development of a medication synchronization common language for community pharmacies (2018) Journal of the American Pharmacists Association, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049319755&doi=10.1016%2fj.japh.2018.04.032&partnerID=40&md5=b7b8efb6581ef421cfd41baa71b017a2
Wang, Y., Farley, J.F., Ferreri, S.P., Renfro, C.P. Do Comprehensive Medication Review completion rates predict medication use and management quality? (2018) Research in Social and Administrative Pharmacy, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049118479&doi=10.1016%2fj.sapharm.2018.06.010&partnerID=40&md5=30f4ab4c896c4b86319be64b8e4e5ac1
Adams, K., Kearney, M., Lee, K., Rhoney, D., Smith, K.M. Strength in Numbers: A Team-Based Approach to Managing Patients with Hyponatremia (2018) American Journal of Medicine, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049587298&doi=10.1016%2fj.amjmed.2018.05.005&partnerID=40&md5=2694cf54161ab3d6b28176121ab3a136
Carpenter, D.M., Dhamanaskar, A.K., Gallegos, K.L., Shepherd, G., Mosley, S.L., Roberts, C.A. Factors associated with how often community pharmacists offer and dispense naloxone (2018) Research in Social and Administrative Pharmacy, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049740073&doi=10.1016%2fj.sapharm.2018.07.008&partnerID=40&md5=bf9121ee32823cf8d5f87eb31cc4c09a
Bellottie, G.D., Kirwin, J., Allen, R.A., Anksorus, H.N., Bartelme, K.M., Bottenberg, M.M., Dula, C.C., Kane, T.H., Lee, P.H., McMillan, A., Riley, B.L., Waghel, R. Suggested pharmacy practice laboratory activities to align with pre-APPE domains in the Doctor of Pharmacy curriculum (2018) Currents in Pharmacy Teaching and Learning, . Article in Press. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049113681&doi=10.1016%2fj.cptl.2018.06.001&partnerID=40&md5=68d272d9405c18a35281014421868ab3
Farley, J.F., Ferreri, S.P., Easter, J.C., McClurg, M.R. The North Carolina Experiment: Active Research in the Development and Assessment of New Practice Models (2017) North Carolina medical journal, 78 (3), pp. 186-190. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049645109&doi=10.18043%2fncm.78.3.186&partnerID=40&md5=eb9cb7034bdad146b383b528647e90a5
Urick, B., Brown, P., Easter, J.C. Achieving Better Quality and Lower Costs in Medicaid Through Enhanced Pharmacy Services (2017) North Carolina medical journal, 78 (3), pp. 188-189. https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049647606&doi=10.18043%2fncm.78.3.188&partnerID=40&md5=2fb5327208758b061c648cf783a7f24c