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Target 2035 - A Probe for Every Protein - Webinar Series - FAO UNC Eshelman School of Pharmacy

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Target 2035 – A Probe for Every Protein – Webinar Series

November 11, 2020 @ 10:00 am - 12:00 pm

WHAT will need to be done for Target 2035

Moderator: Milka Kostic (Dana-Farber Cancer Institute)
Exemplars from the recent past
5 min Milka Kostic (Dana-Farber Cancer Institute) Welcome and introduction
15 min Stefan Knapp (SGC- Goethe University Frankfurt) Expanding the scope of kinase chemical probe development
15 min Cheryl Arrowsmith (SGC- University of Toronto) Chemical Probes to modulate epigenetics: learnings from a 10- year journey
15 min Bryan Roth (University of North Carolina at Chapel Hill) Illuminating the understudied GPCR-ome
10 min Discussion and audience Q&A
Opening up new target areas
15 min Peter Sorger (Harvard University)
Kinase inhibitors: lessons from an extensively targeted druggable protein family
15 min Sara Buhrlage (Dana- Farber Cancer Institute) Target class approach for DUB probe development
15 min Dirksen Bussiere (Eli Lilly) The Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex
15 min Discussion and audience Q&A


November 11, 2020
10:00 am - 12:00 pm


Dottie Forthman